Testosterone Muscle Mass
October 29, 2011 by staff
The loss of muscle mass and strength contributes to frailty and is associated with mobility problems, falls and fractures, the authors say, and men lose more muscle mass and strength than women as they age.
That suggests that the levels of sex hormones, particularly testosterone, may influence the age-related changes in body composition and physical function, according to researchers led by Dr. Erin LeBlanc, Kaiser Permanente Northwest in Portland, Oregon
The study included nearly 1,200 men aged 65 years who had sex steroid levels measured and were followed for an average of 4.5 years. Their body composition was verified byanlysis of high technology, and physical abilities were assessed through exercises that assess lower extremity power, grip strength, walking speed and ability to rise from a chair without using the weapons.
“Our study reveals that men 65 years of age, with higher testosterone levels lost less muscle mass, especially in your arms and legs than men in this age group had lower levels of testosterone,” LeBlanc said in a statement of the Endocrine Society.
“Men with higher testosterone levels before losing the weight he lost the leg and less could function more easily support a chair that men with low testosterone levels before losing weight,” he said.
“The number of men have testosterone in their bodies can contribute to the amount of muscle and strength, lose as they age,” he said LeBlanc.
One expert was not surprised by the findings, but added that there is no reason to urge older men supplemental testosterone.
The study “confirms that increased blood levels of testosterone in older men is associated with less loss of muscle mass that occurs with aging,” said Dr. Stuart Weinerman, chief of the division of endocrinology Health System North Shore-LIJ in New Hyde Park, New York, but noted that “this is a prospective epidemiologic study, not a controlled trial, so that variables may be present. For example, patients with low levels testosterone were more likely to have diabetes. ”
Weinerman added that “this study should not be interpreted as evidence that men with hypogonadism [those with decreased output of testosterone] should begin testosterone replacement. The risks and benefits of testosterone replacement can only be studied in large , randomized controlled trials. ”
Another expert said the levels of testosterone may be necessary to see that men get older.
“Physicians should monitor the levels of testosterone in men over 65 years, speaking of muscle mass loss and the potential for falls and fractures as a result,” said Dr. Spyros Mezitis, an endocrinologist at Lenox Hill Hospital in New York . “More research is needed to define the association of low testosterone levels and decreased physical function,” he said.
The study, funded by grants from the National Institutes of Health, USA, is scheduled to be published in the Journal of Clinical Endocrinology & amp; Metabolism.
Please feel free to send if you have any questions regarding this post , you can contact on
Disclaimer: The views expressed on this site are that of the authors and not necessarily that of U.S.S.POST.