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Scientists Discover Source Of Baldness

March 22, 2012 by staff 

Scientists Discover Source Of Baldness, US researchers identified the protein responsible for male pattern baldness, raising expectations that an effective treatment for the most common cause of hair loss in men is on the horizon.

Male pattern baldness affects eight out of 10 men and causes the hair follicles to shrink and produce microscopic hairs, which grow for a shorter duration of time than normal hairs.

“We looked at bald scalps last year and saw the hair follicles were still present,” according to senior author George Cotsarelis, from the Perelman School of Medicine at the University of Pennsylvania. “So we inferred there was either a lack of an activator [to spur hair growth] or the presence of an inhibitor.”

Using microrays, Cotsarelis and his colleagues took tissue samples from the scalps of men who suffered from androgenetic alopecia and measured levels of different genes. The samples were taken from both bald spots and spots with hair.

The researchers found that the bald spots had abnormally high levels of a protein called Prostaglandin D2 (PGD2) – nearly three times the amount present in the scalp areas with hair.

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