February 21, 2011 by staff
Mononucleosis, Infectious mononucleosis (IM, also known as EBV infectious mononucleosis or glandular fever, or Pfeiffer’s disease or illness Filatov and sometimes colloquially as the kissing disease of oral transmission mono or just as in North America and the glandular fever in other English-speaking countries) is a widespread viral disease caused by Epstein-Barr virus (EBV), a type of herpes virus, in which more than 90% of adults have been exposed. This is not chronic. Most people are exposed to the virus as children, when the disease produces no symptoms or visible only flu-like symptoms. In developing countries, people are exposed to the virus early childhood mostly in developed countries. Consequently, the disease as it is observed more frequently in developed countries. It is more common among adolescents and young adults.
Especially among adolescents and young adults, the disease is characterized by fever, sore throat and fatigue, and several other signs and symptoms. It is primarily diagnosed by observing symptoms, but the suspicion can be confirmed by several diagnostic tests. The syndrome has been described as an infectious process by Filatov Nile in 1887 and independently by Emil Pfeiffer in 1889. Mononucleosis may increase the risk of developing chronic fatigue syndrome in adolescents, according to a study. Previous studies have indicated that about one in ten adults with acute infectious mononucleosis continue to develop chronic fatigue syndrome, Dr. Ben Z. Katz, Northwestern University Feinberg School of Medicine, Chicago, and colleagues write. Katz and other researchers followed more than 300 teenagers from the disease. About 13 percent of the original study developed chronic fatigue syndrome. During a 12-month follow-up visit, 7 percent had chronic fatigue syndrome, and 24 months, chronic fatigue syndrome has persisted in 4 percent. “In our study, we also followed a group of teenagers who have completely recovered from their mononucleosis, Dr. Katz told Reuters Health. “We are now trying to understand what differentiates adolescents who recover from those who have not,” he said.
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