February 8, 2011 by staff 

DMAE, U.S. scientists have discovered the key to one of the main causes of macular degeneration (DMAE). According to research by the University of Kentucky, published in the journal Nature, there is an enzyme, known as DICER1, which is less active in the retina of patients with so-called geographic atrophy, and corresponds to the later stages of the dry form of the disease.

In this regard, DICER1 found that the enzyme is responsible for destroying small amounts of Alu RNA, a genetic material that when accumulated causes high levels of toxicity and leads to death of cells in the macula of the retina, which are responsible central vision and visual acuity.

For Professor Jayakrishnan Ambati, director of the study, “these results require further understand the biological processes that lead to reduced levels DICER1 and the precise origin of Alu RNA, for future treatments.”

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